The equation of piezoelectric sensor and piezoelectric actuator were derived in the process of investigating the optimal placement of piezoelectric actuator for active vibration control of the intelligent structure firstly,then the smallest energy as the objective function and the position coordinate of the piezoelectric actuator were taken as the variabl according to the energy criterion,the locations of the piezoelectric actuators were optimized.Finally,the optimal placements of the piezoelectric actuators were calculated by matlab.The vibration control of structure had become true through compiling the program of APDL(ansys parameter design language) and using transient dynamic analysis.The simulation investigated that this approach had more effective in suppressing the vibration of the intelligent beam in this paper.