Using software FLUENT in the RNG κ-ε turbulence model with Reynolds number 20000 and spacing ratio s/d equaling to 1.75,this article simulates two cylinders' drag and lift coefficients in four engineering conditions,as the two cylinders are set in serial,in parallel,as well as there are angles of 30 and 60 degrees between the line connecting column centers and the flow direction.The acquired conclusions are as follows: The drag coefficient increases with the increasing angles,which reaches maxim when the cylinders are in parallel,while it is minus with the cylinders in serial;as to the lift coefficient,the integral is not equal to 0 besides the two cylinders are in serial.