In order to get the similar material rock model with high gravity, low strength and low modulus, the method of orthogonal experimental is used to analyze the material parameters sensitivity of rock-like sample with iron crystal sand. The percentage of aggregate content, the weight ratio of iron powder to barite powder, the weight ratio of iron powder plus barite powder to quartz sand with coarse particle and fine particle and the weight ratio of cement to plaster are selected as four-factor, three-level. Nine sets of material proportion plans are designed. Through weight, measure and uniaxial compression test, the parameters of density, compressive strength, elastic modulus and peak strain are obtained.. The range analysis is used to analyze the sensitivity of various factors. The results show that:the weight ratio of iron powder plus barite powder to quartz sand with coarse particle and fine particle mainly influences density and elastic modulus; the percentage of aggregate content mainly influences compressive strength; the weight ratio of iron to barite powder mainly influences peak strain; The influence of other factors is not obvious.