In order to study the dynamic response of silo frame and its equivalent model under earthquake action, this paper intends to simplify the silo into column ring beam structure according to the principle of stiffness equivalence in combination with the degassing and storage silo frame structure project of a petrochemical coMPany. By changing the cross-section size of column ring beam and the number of ring beam, the finite element models of silo frame structure and column ring beam frame structure are established, and the reasonable column ring beam frame model is selected to simulate the original structure. On this basis, the equivalent increase coefficient of stiffness is determined to be 1.25. Using time history analysis method, three seismic waves, El Centro wave, Taft wave and artificial wave shm2 wave, are selected to give the maximum displacement and maximum equivalent stress seismic response of the structure under three working conditions.