In order to realize the real-time settlement analysis of interlaction process between miscellaneous fill and soft soil foundation and explore the effect of coarse particle content of soft soil on the interbedded settlement and the consolidation settlement of soft soil, with the help of self-developed interbedded test instrument of miscellaneous fill and soft soil, the interbedded settlement and consolidation settlement of soft soil were quantitatively distinguished through laboratory tests. Orthogonal experimental groups were designed to analyze the settlement development rule of two kinds of miscellaneous fill particles (5 mm, 10 mm) and five kinds of coarse particle content soft soil (0, 3%, 6%, 9%, 12%) under a certain load, and to summarize the differences of final settlement and instantaneous settlement of total settlement, interbedded settlement, and consolidation settlement of soft soil. The experimental results show that when coarse particles exist in soft soil, the total settlement and interbedded settlement increases more and develops faster than that those without coarse particles in each stage, and the total settlement and interbedded settlement reach a maximum value when coarse particles content is 6%. Besides, the influence of the coarse particles content on consolidation settlement of soft soil is not obvious.