In order to explore the effect of dry-wet cycles on the mechanical properties of self-compacting soil-cement, the unconfined compressive strength of self-compacting cemented soil under different dry-wet cycles was compared and analyzed through experiments, and the appearance damage degree and strength deterioration law of self-compacting cemented soil were discussed. According to the strength decay law, an empirical formula between the dry-wet cycle number and strength deterioration was established. It is found that the strength decay rate of self-compacting cemented soil after the j_th dry-wet cycles is j^0.3 times that of the first cycle. The peak strength of the stress-strain curve of self-compacting cemented soil gradually decreases with the increase of the number of dry-wet cycles, and the failure type of sample changes from brittle failure to plastic failure.