A multi energy complementary system based on aquifer reservoirs was constructed, and the temperature response characteristics of the aquifer multi energy complementary system and the temperature variation law of the production well were analyzed. The influences of the reinjection temperature, bottomhole pressure difference, and well spacing on the temperature of the production well were explored. Finally, the significance of each factor was analyzed through the response surface methodology. The results indicate that the system can effectively extend the service life of geothermal wells and achieve the function of outputting stable energy by exchanging and balancing fluctuating energy through heat exchange within the formation. Increasing the reinjection temperature can slow down the decrease in temperature of the production well. Increasing the bottomhole pressure difference can shorten the equilibrium heat production time and accelerate the temperature drop of the production well. Increasing the well spacing can prolong the stability time of the production well and slow down the temperature drop of the production well. With the response surface analysis method, the primary and secondary order of the four factors affecting the water temperature of production wells was analyzed as: well spacing>bo-ttomhole pressure difference>reinjection temperature>service life. The interaction between reinjection temperature and well spacing had the greatest impact.