With the advantages of environmentally friendliness, high strength-to-weight ratio and good seismic performance, glulam has been widely applied to modern structures. The glulam space frame structure is a representative large-span spatial structure. In this paper, the main existing forms of glulam space frame structures are summarized and classified based on practical engineering applications. A comprehensive review of the main research advances of the glulam space frame structure is presented and mainly expounded from the aspects of mechanical behaviors of joints and overall structures. Several issues that should be paid attention to the study of overall structures were proposed. Finally, the further researches worth investigating were put forward. This paper has certain reference significance for the research and can also promote the development of relative engineering applications.