Based on adjusting the plane layout of shear wall with a frame-shear wall structure,the modal of each plane layout scheme was analyzed by using Sap2000 and the seismic action was calculated by using response spectrum method. The influence of plane layouts of shear wall on frame-shear wall structure seismic response was investigated. It was found that the seismic performance of the improved model was significantly improved,and the longer the distance of shear walls to the center of rigidity was,the better the torsional effect will be. The reasonable shear wall layout could effectively improve the seismic performance of a frame shear structure.