In order to improve the effect of heat and mass transfer, studying the influence laws of heat and mass transfer effect of various factors is of great significance to improve the efficiency of heat and mass transfer of spray chamber. This paper adopted the numerical simulation method, and carried out the contrast research of the water-drop law of motion and effect of air-water heat moisture transmission in vertical spray chamber which have two kinds including the upward-spray type and the downward-spray type. The result shows that not only the water residence time, but also the heat transfer effect the upward-spray type is superior to the downward-spray type.