Taking the high-tech industries and high energy-consuming industries as examples, green innovation efficiency of high-tech industries and energy-intensive industries in Beijing-Tianjin-Hebei region from 2009 to 2016 was measured by using super efficiency SBM model that considered undesired output. On this basis, the least square regression model was used to study the relationship between green innovation efficiency and environmental regulation in Beijing-Tianjin-Hebei region. The results show that the green innovation efficiency of Beijing and Tianjin is much higher than that of other cities in Hebei province. And the green innovation efficiency of high energy-consuming industries in Hebei province is higher than that of high-tech industries. Besides, the green innovation efficiency of high-tech industries is negatively correlated with environmental regulation, negatively correlated with openness, and positively correlated with enterprise scale and r&d intensity. The green innovation efficiency of high energy-consuming industries are positively correlated with environmental regulation, negatively correlated with openness, and positively correlated with enterprise size and r&d intensity.