Based on the analysis of the engineering geological environment background of transmission iron tower foundation on Wufeng mountain in Zhenjiang, FLAC3D three-dimensional numerical simulation software and strength reduction method were used to analyze the deformation characteristics of the tower foundation slope under five working conditions of natural wind, strong wind 90°, strong wind 60°, strong wind 45ånd strong wind 0°. The stability coefficient of the tower foundation slope under each working condition was also calculated. The results show that the overall uneven settlement of tower foundation slope foundation under the conditions of natural wind, strong wind 90°, strong wind 60°, strong wind 45° and strong wind 0° are respectively:0.43‰, 0.66‰, 0.50‰, 0.33‰, 0.65 ‰. The slope stability coefficients are respectively:1.31, 1.25, 1.23, 1.23, and 1.18, indicating that the slope is in a stable state under five operating conditions. The stability of the foundation slope is relatively small when the wind is 0°.