In the process of promoting innovative national construction, intellectual property is the key. At current the intellectual property talent is of shortage, the hierarchical structure is unreasonable, the knowledge structure is not comprehensive. The emergence of these problems is due to the fact that China's traditional intellectual property education is limited to the legal profession. With China's economic and social development, only the professional background of law can not meet the needs of society, enterprises and organizations need is talent of polytechnic background, and proficient in intellectual property law knowledge comprehensively. This paper analyzes the science and engineering colleges in compound intellectual property advantages of talents cultivation, and puts forward the training program of the intellectual property talents in the science and engineering college.