in the rapid development of China's economy today, the demand for talent in the society is constantly im proving, especially for the professional quality of the comprehensive talent has a relatively high requirements. Coll ege English as one of the required subjects, students in the learning process, there is a certain difficulty. At the same time, the traditional college English teaching mode in the actual application process has certain drawbacks, College English teaching mode in CBI theme based on Application of paying more attention to cultivating practical English ability of college students, not to learn English grammar for teaching focus, teachers in the teaching process to inc rease efforts to train students' English listening speaking, reading and writing ability, with modern teaching methods also have very positive significance to improve the effectiveness of College English teaching. And then the author will combine their own teaching experience, the use of CBI theme teaching model in College English Teaching in the application of the effectiveness of the relevant experimental research, in order to provide reference for future tea ching use.