This article has analyzed the influencing factors of library resource, constructed the evaluation index system of library collection resources, put forward the application of fuzzy mathematics comprehensive evaluation method, hierarchically to determine the degree of membership of the library, and combined with the Analytic Hierarchy Process method, each two indexes are compared by experts in the field of library, in order to determine the evaluation of each level relative to the upper level weights, evaluate library resource fully, determine the final score, which makes the result more objective, scientific. Finally, through examples, the use of evaluation is illustrated detailedly.