This paper elaborated the CDIO engineering education concept, training program and Implementation measures in the perspective of the teaching reform and practice of computer basic course and how to combine the theoretical knowledge and the training of students' application ability. Through teaching reform and practice of computer basic course, the author helps students set up the CDIO engineering education thought from they starting school, and lay a good foundation for the students to study follow-up courses. So that university-trained talent is more in line with the needs of the society.