Abstract: TV talk shows have been favored by more and more audiences since 1950s. "The Ellen Degeneres Show" is one of the most popular talk shows in America. Pragmatic Presupposition increasingly arouses more and more attention among linguists, which is applied frequently in talk shows. This paper analyses the application of pragmatic presupposition in talk show and finds out the four types of pragmatic presupposition as well as its function in talk show to help audiences appreciate talk show better.