This paper analyzes the current situation of basic computer courses taught in college education, and the corresponding reform program carried out in the new teaching mode of CDIO is to make the students adapt better to the needs of the technological information development in the future. Course construction is the key for teaching reform. The key for teaching reform of the basic computer course is to nurture their computational thinking ability,whose theoretical basis is to build the computer application ability for the individual's sustainable development.The first undergraduate computer science course----Computational Culture and Computational Thinking Foundation is elaborated carefully, which is aimed for localization and characterization, based on computational thinking as a focal point and oriented with nurturing students' information consciousness.