Handan is a national famous city with long history and culture. It is located in the southern part of hebei province, shanxi-hebei-shandong-henan area over the four provinces and the central plains economic zone centre, Handan is an important part in the hebei economic development due to its rich mineral resources. Relying on its unique advantages, the economy develops constantly. But in the new situation, its economic development is faced with many difficulties and challenges. This article is mainly about handan industry development and its pillar industry based on the advantage of resources. Under the beijing-tianjin-hebei regional integration background, there are lots ofopportunities and challenges for handan to adjust its industrial structure. Moreover, it points out how to transform and upgrade the handan's industrial structure in the future. Through analysis of the handan's industry problem, I hope that it can provide certain reference to the handan industry development for the future.