Under the background of new medical and health care systems, from the view of Party's Mass Line's basic meaning, this paper mainly discusses the significance of medical and health institution to persist Party's Mass Line. It requests medical and health institution to persist Party's Mass Line with the developing view, to grasp rightly Mass Line's new features and new cases. The medical and health institution should do the work of Mass Line with pragmatic style. On this basis, the writer proposes the corrsponding ideas and suggestions of how to persist Party's Mass Line.