In the new situation, reforming the higher education to improve the quality of personnel training is to reform and innovate the training mode of professional talents. Focusing on the training goal and basic requirements, the paper elaborates on comprehensive reform practices of the mechanical design and manufacturing and automation specialty from the aspects of development of professional training programs,establishment of curriculum based course-groups,creation of the personnel training mode,and so on.It has some inspiration and guidance in teaching reform and personnel training for other colleges and universities.