Under the background of science and technology development and innovation in the new period, it is the objective requirement to deepen the industry-university-research cooperation and collaborative innovation. However, there is insufficiency in China's universities and colleges carrying out the integration of the value orientation, evaluation mechanism, technology transfer, profit distribution, and policy support and so on. Therefore, to further strengthen the industry-university-research cooperation and collaborative innovation and promote the development of science and technology innovation, the universities and colleges in China should increase their science and technology innovation, improve economic and social development, strengthen personnel training and the connotation of teachers' team construction, set up a cooperative and innovative research and development mechanism of industrial technology, and the government should optimize its policy support, etc.