As a burgeoning open online learning system, Mooc appeared and is developing globally, providing a brand new vision and learning experiences for the globalization of higher education. It has a strong influence on the long distance open education as well. How does University of Phoenix (UPX), a good model of long distance education in USA, with a history of 40 years, cope with such a trend? This paper analyzes its development features and coping strategies and thus gives some thoughts and suggestions on its development in China.