In the overall trend of globalization, college students are required to be qualified with cross-culture communication skill. With the integration of world economy, cross-culture communication is not only applied to foreign languages but also to the business field, thus arises the demand for business cross-culture communication talents. This article starts with in-class teaching, analyzes the existing issues in the business cross-culture communication teaching process from the aspect of teaching mode, so as to carry out corresponding suggestions for cross-culture business communication competence cultivation.