New goals of cultivating mechanical engineering talents should be combined with Chinese manufacturing 2025 and the industrial background of the requirements of 4.0 to enhance the students' engineering literacy and innovation ability.This paper starts from the problems encountered in the construction of the practical teaching system of mechanical specialty,and constructs a new practical teaching system in stages,levels,modularity and variety in order to implement the practical teaching,establish all-round,multi-angle quality guarantee and monitoring system,and cultivate the talents with engineering practice and innovation ability.