In the excellent long river of the Chinese nation,the combination of Chinese communist party and marxism-leninism conformed to the development history of China, leading the Chinese nation to overthrow the three mountains that pressed on the Chinese people. In the process, the red gene created by the Chinese Communist Party was highly integrated with the excellent culture of China, complied with the law of historical development, and formed a red gene with Chinese characteristics. The red gene contains the proletarian theory, the excellent revolutionary tradition, the noble moral quality, and so on. On the way of realizing China's dream, we should inherit the red gene, adhere to the red gene inheritance and variation of unity, to prevent any red gene mutation, grasp the direction of red gene of the development of the proletariat, in order to make the red genes always lead the Chinese nation excellent culture, set up culture confidence, provide the spirit food for Chinese dream.