Based on the characters of research teaching, and combined with the nature of Mechanism Manufacture Technology Basis, the research teaching exploration and practice is carried out through teaching content, classroom teaching, practical teaching, and course examination.When the results are applied to the majors such as mechanical design manufacturing and automation, mechanical and electrical engineering, vehicle engineering and so on, it is shown that students' learning enthusiasm in relevant professions has been improved, independent findings and problem solutions have also been enhanced significantly, and the theoretical knowledge is strengthened and compacted.