independent innovation is the source of enterprise vitality and the core element of sustainable competition. Based on 30 listed companies in hebei province as the research object, based on the panel data of 2013-2017, by using the grey correlation model analysis enterprise independent innovation ability, the result of the model by using entropy - mutation series, using the coupling test enterprise innovation performance, enterprise scale and innovation to the synergistic effect between incentive motivation, analyses three factors and the influence degree of the synergy of enterprise independent innovation. The research shows that:(1) the key element of building enterprise independent innovation ability is enterprise innovation performance, which can significantly improve enterprise independent innovation ability; (2) business environment and innovation motivation have a significant positive impact on improving the independent innovation ability of enterprises.