Wholeness is the prerequisite ideological and political theory course teaching in colleges and universities. From the point of view of subject knowledge, Mao Zedong's thought, Deng Xiaoping's theory, Xi Jinping's new era conception and so on, follow the requirement of unity of historical logic, and have internal unity in knowledge content, theoretical achievements and teaching system. Therefore, teachers should grasp the overall layout of teaching materials, change their ideas, adjust their teaching ideas, firmly believe in Marxism, and enhance the persuasion, influence and conquest of theoretical course teaching. Based on the basic principles of Marxism as a whole, teachers should grasp the intrinsic logic and theoretical value of "Introduction" course, and ensure the orderly achievement of curriculum objectives.