In the new era, the problems of university students' belief in the new era are mainly manifested in five aspects:belief pluralism, belief utilitarianism, belief irrationality, belief cognition and belief behavior fragmentation, and belief deficiency. The reasons are very complex. There are not only profound social and historical reasons at home and abroad, but also reasons for the lack of university education and the weakness of university students themselves. We should adhere to the problem orientation and goal orientation, coordinate and utilize various famous and excellent "medicinal materials" and "physiotherapy equipment" actively from three aspects:First, we should "suit the right medicine to the right situation", strengthen the positive instillation of Marxism, carry forward the core values of socialism, and strengthen the practical education function; second, we should "comprehensively adjust", make good use of modern information technology, pay attention to the guidance of campus culture, play the role of the whole society in educating students in coordination, and strengthen the construction of teachers' morality and style; third, we should "treat both the symptoms and the symptoms" and build a long-term system and mechanism that can make contributions for a long time.