Under the background of "double first-class", the exploration of innovative talent training mode is a long-term and complex project, which requires not only the efforts of universities, but also the support of students and teachers. This paper expounds the exploration and practice of the training mode of innovative talents in colleges and universities under the background of "double first-class" from the policy formulation from higher authorities, the comprehensive quality of the teacher team, the students to consolidate the foundation of three aspects, clarifies the training mode of innovative talents in colleges and universities, understands the influence of each link on innovative talents, and establishes a perfect education mode for the training of innovative talents in the new era.