In order to study the collaborative development of logistics industry and economy in Handan City, this paper selects the logistics and economy indicators of Handan city from 2012 to 2019 to establish the index system, analyzes the key factors affecting the development of logistics and economy in Handan city by using the grey correlation model, and analyzes the collaborative development degree of logistics and economy in Handan City in recent years by using the coupling coordination model. The results show that there is a high degree of correlation between the logistics industry and economic factors in Handan, among which the highway mileage and the total amount of post and telecommunications business are the key factors affecting the economic development, and the value of secondary industry and GDP are the key factors affecting the logistics development; at present, the logistics industry and economy of Handan city are in the stage of barely coordinated development, so it is necessary to further promote the coordinated development of the two. On this basis, the paper puts forward relevant suggestions for the coordinated development of logistics and economy in Handan.