Weishi Jiacangfang is a private book written by Wei Xian in his hometown Bixi Yinzhou of Siming (now Ningbo), Zhejiang in 1227 in the Southern Song Dynasty. The circulation of this book has experienced multiple ups and downs since its publication. In this paper, the writer looks at its spread and preservation in China in chronological order and reveals three major points, namely, the fate of the book is closely related to its publication, preservation and research; there is a long way to go before the return of precious ancient Chinese medical books from overseas; the discovery and compilation of ancient Chinese medical books is the basis for inheriting traditional Chinese medicine and promoting the culture of Chinese medicine.