As an important means of stabilizing the financial system, macro-prudential policies have been practiced in China for a long time, but the effects of specific policies have yet to be explored. This paper uses the data of 16 listed banks in China from 2012 to 2019 to construct an indicator reflecting the contribution of the bank's systemic risk, and then uses the system GMM to analyze the effect of macro-prudential policies in suppressing the contribution of the bank's systemic risk. The research results shows that the overall implementation of macro-prudential policies can effectively suppress the contribution of banks to systemic risks, and the effect of implementation is positively correlated with the intensity of policies. In addition, the macroeconomic environment and the bank's own variables will also have a differentiated impact on the contribution of banks to systemic risks. Further research also shows that the implementation of countercyclical macroprudential policies is conducive to reducing systemic risk fluctuations caused by economic cycle changes and smoothing the economy cycle. Therefore, macro-prudential policies should be mainly implemented counter-cyclically, and special attention should be paid to the five major state-owned banks, and when necessary, requirements can be put forward for the indicators of commercial banks themselves.