New subjects put forward higher requirements for talent cultivation. Taking the public practice base of innovation and entrepreneurship education for food science students jointly built by Hebei Engineering University and Chenguang Biological Group as an example, integrating the resource advantages of universities and scientific and technological enterprises, constructing the training mode of innovative and entrepreneurship talents for food science majors jointly trained by Universities and enterprises, and forming the public practice of innovation and entrepreneurship education. Base process management system provides innovative entrepreneurship projects for students majoring in food science, and promotes the cultivation of innovative and diversified talents in food science. It aims to provide theoretical and practical reference for innovative entrepreneurship education for students majoring in other engineering disciplines.